Abstract:
Objective To understand the characteristics of the carboxyl terminal gene of measles virus N gene in Anhui Province from 2017 to 2021.
Methods RT-PCR was used to amplify the 450bp fragment of nucleotide in N gene of measles virus. The nucleotide sequence and gene characteristics of the amplified products were analyzed.
Results From 2017 to 2021, 47 measles virus strains of H1 genotype, 2 measles virus strains of D8 genotype, 1 measles virus strain of B3 genotype and 15 measles virus strains of A genotype were detected in Anhui.
Conclusion From 2017 to 2018, H1 genotype was predominant in measles virus strains in Anhui. After 2018, no H1 genotype strain was detected. Imported measles cases caused no epidemics. It is necessary to further strengthen the identification of measles pathogens in Anhui for the timely detection of imported measles cases and stop virus transmission.