Abstract:
Objective To understand the source of infection, time of infection and related factors in newly reported HIV infection and AIDS patients.
Methods The newly reported HIV/AIDS in Nanjing from January 1, 2020 to June 30, 2022 was recruited as research objects. Demographic characteristics, behavioral characteristics, possible sources of infection and time of infection were collected by case-tracing questionnaires. New infection was defined as a history of HIV negative testing within 1 year prior to confirmation, or a history of negative testing within 1.5 years with high-risk behavior within the last 1 year, or a first time CD4+T lymphocyte count of ≥500/μL.
Results A total of 1119 subjects were collected. Among the cases whose infection location could be determined, 80.19% were infected in Nanjing. 55.76% were newly infected among 1119 cases. Multivariate logistic regression analysis results showed that female, high school or technical secondary school or vocational school education, non-students, people who lived in Nanjing for more than half a years and people infected through homosexual sexual behavior were determined to be the relevant factors of local infection. Aged 24 years and younger, married, secondary school education or above, number of unmarried sexual partners in the 1 year before diagnosis was ≥2, HIV antibody test before diagnosis, age of the first sexual behavior was ≥ 18 years old were determined to be the relevant factors of new infection.
Conclusion Newly reported HIV/AIDS in Nanjing from 2020 to June 2022 were mainly local infection and new infection. In the future, we should focus on local high-risk population intervention in Nanjing, and formulate detection strategies according to the characteristics of non-newly infected population, to further increase the proportion of early detection.
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