高雄, 李园园, 郝林会, 邓淑珍. 云南省景洪市某学校一起诺如病毒GⅠ、GⅡ混合感染引起的胃肠炎暴发疫情的调查[J]. 疾病监测, 2023, 38(8): 1014-1017. DOI: 10.3784/jbjc.202303090096
引用本文: 高雄, 李园园, 郝林会, 邓淑珍. 云南省景洪市某学校一起诺如病毒GⅠ、GⅡ混合感染引起的胃肠炎暴发疫情的调查[J]. 疾病监测, 2023, 38(8): 1014-1017. DOI: 10.3784/jbjc.202303090096
Gao Xiong, Li Yuanyuan, Hao Linhui, Deng Shuzhen. Investigation of an outbreak of gastroenteritis caused by co-infection of norovirus G and G in a school in Jinghong, Yunnan[J]. Disease Surveillance, 2023, 38(8): 1014-1017. DOI: 10.3784/jbjc.202303090096
Citation: Gao Xiong, Li Yuanyuan, Hao Linhui, Deng Shuzhen. Investigation of an outbreak of gastroenteritis caused by co-infection of norovirus G and G in a school in Jinghong, Yunnan[J]. Disease Surveillance, 2023, 38(8): 1014-1017. DOI: 10.3784/jbjc.202303090096

云南省景洪市某学校一起诺如病毒GⅠ、GⅡ混合感染引起的胃肠炎暴发疫情的调查

Investigation of an outbreak of gastroenteritis caused by co-infection of norovirus G and G in a school in Jinghong, Yunnan

  • 摘要:
      目的   调查云南省景洪市一起由诺如病毒引起的学校急性胃肠炎疫情,为诺如病毒的防控提供依据。
      方法  采用现场流行病学调查方法和个案调查,收集云南省景洪市某小学基本情况和患病学生相关信息资料进行流行病学特征分析,采集肛拭子标本、食物和饮用水进行引起腹泻病毒核酸检测。 率的比较采用χ2检验。
      结果  2023年2月19—22日,累计搜索到24例病例(男生16例,女生8例),罹患率为4.05%,男女生罹患率分别为5.13%(16/312)和 2.85%(8/218),差异无统计学意义(χ2 =1.981,P=0.159);流行曲线提示为点源暴露,主要集中在四年级共14例,占58.33%,与其余年级差异有统计学意义(χ2 = 15.563,P=0.008);发病较多的3个班级均分布在教学楼二楼左侧,与其余班级差异有统计学意义(χ2=27.449,P=0.002);症状以腹泻(100.00%)、腹痛((95.83%)为主。 病例对照研究发现,接触按压式桶装水后不洗手是造成本次疫情传播的主要因素,与发病存在统计学关联,比值比(OR)为12.14。 32份肛拭子样本中7份为诺如病毒阳性(其中4份GⅡ型,3份GⅠ型)。
      结论   此次暴发疫情可能为一起学生返校时引起的输入性诺如病毒GⅠ、GⅡ混合感染疫情,因云南枯水期学生不洗手或洗手不到位导致疫情传播扩散。

     

    Abstract:
      Objective  To investigate an outbreak of acute gastroenteritis caused by norovirus in an primary school in Jinghong, Yunnan province, and provide evidence for the prevention and control of norovirus infection.
      Methods  Field epidemiological survey and case survey were conducted to collect the basic information of the school and case information in Jinghong, Yunnan province. Anal swabs of the cases, food and drinking water samples were collected for enterovirus nucleic acid detection. The comparison of the rates were done by χ2 test.
      Results  During February 19–22 , 2023, a total of 24 confirmed cases of acute gastroenteritis were reported, including 16 girls and 8 boys, with an attack rate of 4.05%. The attack rate was 5.13% in girl students and 2.85% in boy students, the difference was not significant (χ2=1.981, P=0.159). The epidemic curve indicated a point source outbreak, 14 cases occurred in grade 4, accounting for 58.33%. The difference was significant compared with other grades (χ2= 15.563, P=0.008). Three classes with more cases were all distributed on the left side of the second floor of the teaching building, the difference was significant compared with other classes (χ2=27.449, P=0.002). The main symptoms were diarrhea (100.00%), abdominal pain (95.83%). Case-control study showed that failure to wash hands after pressing button of water container was the main factor causing the spread of the epidemic, showing a statistical association with the incidence of the disease (OR=12.14). In 32 anal swabs, 7 were positive for norovirus (4 were positive for GⅡand 3 were positive for GⅠ).
      Conclusion  This outbreak might be caused by co-infection of norovirus GⅠand GⅡ imported by students returning from vacation and spread due to poor hand hygiene of students in dry season.

     

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