Abstract: In July 2023, a total of 74 infectious diseases were reported globally, affecting 236 countries and regions. Except for influenza, the top five infectious diseases affecting greatest number of countries and regions were COVID-19 (236), monkeypox (113), dengue fever (29), measles (27) and cholera (19). The top five infectious diseases with highest case fatality rates were Middle East respiratory syndrome (35.9%), Lassa fever (16.9%), Crimean-congo hemorrhagic fever (9.8%), West Nile disease (7.3%) and meningitis (6.3%). The top five infectious diseases with greatest number of deaths were COVID-19, dengue fever, cholera, measles and Crimean-congo hemorrhagic fever. The prevalent infectious diseases in Asia were COVID-19, cholera, monkeypox, Crimean-congo hemorrhagic fever and dengue fever, the prevalent infectious diseases in Africa were COVID-19, cholera, yellow fever, Lassa fever, monkeypox and meningitis, the prevalent infectious diseases in America were COVID-19, dengue fever and monkeypox, the prevalent infectious disease in Europe was West Nile disease.