内蒙古自治区35～75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究

徐肖倩; 夏远; 李海玲; 张楠; 曹宁; 张星光

doi:10.3787/jbjc20230020

内蒙古自治区35～75岁居民中心型肥胖与心血管代谢性疾病和共病风险的关联研究

Association between central obesity and cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35−75 years in Inner Mongolia

摘要

摘要:
目的分析内蒙古自治区（内蒙古）35～75岁居民中心型肥胖与心血管代谢性疾病和共病的关联。
方法选择2015年9月至2017年6月“心血管病高危人群早期筛查与综合干预项目”中内蒙古招募的35～75岁居民为研究对象。采用SPSS 25.0和GraphPad Prism 5软件进行统计分析，采用统计描述、χ²检验和logistic回归分析中心型肥胖对心血管代谢性疾病（高血压、糖尿病、血脂异常）和共病的影响。
结果内蒙古35～75岁居民中心型肥胖率为66.5%［95%置信区间（CI）：66.2%～66.7%］，年龄、性别标化率为64.6%。同一个体患有0、1、2和3种心血管代谢性疾病的构成比分别为28.8%、40.5%、23.8%和6.9%。 Logistic回归分析结果显示，轻度中心型肥胖和重度中心型肥胖者高血压、糖尿病、血脂异常、共病的患病风险分别是非中心型肥胖者的1.873和3.093倍、1.876和2.764倍、2.227和3.412倍、2.526和4.419倍（均P<0.001）。
结论中心型肥胖是内蒙古严重的健康问题，是心血管代谢性疾病和共病的危险因素，可进一步加剧心血管疾病负担。因此，应加强中心型肥胖的早期筛查和干预。

Abstract:
Objective To analyze the association between central obesity and cardiometabolic diseases or cardiometabolic comorbidity in residents aged 35–75 years in Inner Mongolia autonomous region.
Methods Residents aged 35–75 years recruited in “Early Screening and Comprehensive Intervention in Population at High Risk for Cardiovascular Diseases” in Inner Mongolia from September 2015 to June 2017 were selected for the study. Statistical analysis was performed by using software SPSS 25.0 and GraphPad Prism 5, mainly statistical description, χ² test and logistic regression analysis, to understand impact of central obesity on cardiometabolic diseases (hypertension, diabetes, dyslipidemia) and cardiometabolic comorbidity.
Results The prevalence rate of central obesity was 66.5% (95%CI: 66.2%–66.7%), and the standardized rate was 64.6% in residents aged 35–75 years in Inner Mongolia. The proportions of persons with 0, 1, 2 and 3 cardiometabolic diseases were 28.8%, 40.5%, 23.8% and 6.9%, respectively. The results of logistic regression analysis showed that the risk for hypertension, diabetes, dyslipidemia and cardiometabolic comorbidity were 1.873 times and 3.093 times, 1.876 times and 2.764 times, 2.227 times and 3.412 times, 2.526 times and 4.419 times higher in people with mild central obesity and severe central obesity than in those without central obesity (all P<0.001).
Conclusions Central obesity is a serious health problem in Inner Mongolia, and it is a risk factor for cardiometabolic diseases or cardiometabolic comorbidity, Therefore, we should strengthen the early screening of central obesity and conduct intervention.

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