Abstract: Objective To understand the incidence trend and characteristics of intestinal infectious diseases in Longgang, Shenzhen and provide evidence for developing control strategy. Methods Descriptive epidemiological analysis was conducted on the incidence data of intestinal infectious diseases in Longgang from 2005 to 2010. Results A total of 37 508 cases of 9 intestinal infectious diseases were reported during this period with the average annual incidence of 197.54/lakh, accounting for 44.27% of the total cases of notifiable infectious diseases. No cholera and poliomyelitis cases were reported. Eight cases were fatal. The mortality was 0.068/lakh. The incidences of hand-foot-mouth disease and other infectious diarrheal diseases varied greatly, but the incidences of hepatitis A,hepatitis E, unspecified hepatitis,bacillary dysentery, amebic dysentery and typhoid/paratyphoid remained stable. The cases mainly occurred in spring and autumn and peaked during May-July and during October-December, accounting for 31.53% and 35.53% of the total respectively. The male to female ratio of the cases was 1.76∶1. The cases in age group of 0-5 years accounted for 79.37% of the total. Conclusion The incidence of intestinal infectious diseases was in increase in Longgang from 2005 to 2010, but the diseases mainly occurred sporadically. It is necessary to take appropriate measures to prevent and control the outbreak of intestinal infectious diseases.