Analysis on Epidemiological Surveillance of HBV Antibody of Different Crowd in Rizhao City 2002

Objective To explore the HBV mark’s changing tendence in Rizhao City.Method To adopt the simple random sampling method to investigate 405 persons of different age in Donggang district; and to collect 2 ml of vein blood to examine HBsAg and anti-HBs with ELA method.Results The average rate of HBsAg carrying was 2.96%,and the highest rate of HBsAg crrying was in the group of 20-40 years old(5.46%).There were no significant different among other groups.Meanwhile,the average positive rate of anti-HBs was 60.99%,the highest positive rate was in the group of <2 years old (81.54%),and the lowest positive rate was in the group of 8 years old. There was a statistical significant different between them. In people who had HBV vaccine immunity experience,the positive rate of anti- HBs was 62.50%,and in those who hadn't HBV vaccine immunity experience was 36.07%,Conclusions The inoculability of HBV vaccine was proved to be efficacious against HBV,but positive rate of anti-HBs declined rapidly after 4 years of HBV vaccine inoculability. In order to improve the positive rate of anti-Hbe, it was necessary to augment immunity to neonates who were negative of anti-HBs after 5 years of the whole course of HBV vaccine in-ocubalityl Otherwise,it wasn't neccssary to apply augmenting immunity after 10 years.