Analysis on Enterovirus Infections of Acute Flaccid Paralysis Cases in Yulin

Objective This smdy was designed to understand entemvims infections and their epidemiological characteristics of acute flaccid paralysis (AFP) cases in Yulin city to provide a scientific evidence for the formulation of AFP surveillante strategies on the maintenance of poliomyelitis eradication．Methods Epiderniologieal analysis was used to classify the AFP cases in whom enteroviruses were detected in their faces from 1996 to 2004 in Yulin city．and the relationship between their immunization history，genders and ages，and etiology was analyzed Results Fecal samples of 251 cases of AFP were tested from 1996 through 2004 and 55 strains of enteroviruses were isolated with an isolation rate of 21.91％ Of the isolated．There were 14 poliomyelitis viruses (Pv) which were vaccine-related strains，including 7 strains of type II viruses (50％)：The isolation rate of PV in cases of AFP with no immunizafion of oral attenuated ive polio vaccine was higher than that of those immunized once to twice and higher than or equal to that of those immunized three times for the disease，wim the rate being 20.00％，17.86％ and 3.40％，respectively．Niteen cases of EV infection menifested residual paralysis 60 days after the onset of the disease And residual paralysis was seen in six cases of PV lnfection．Four of whom were of type II．Accounting for 66.67％．The residuai paralysis rate was higher ha tIIe cases of PV infecfion with zero oral polio—virus vaccille immunization than in those with l to 2 immunizations and still hisher than ib those with 3 or more immunizations．Also．41 strains of non-poliomyelitis entemviruses (NVEV) were detected with the incidence higher in rural areas than in towns．Conckmion There have been no cases found caused by wild poliomyelitis viruses for 12 years in Yulin city．Atier polio eradieation having been confirmed．The study on PV and NPEV is to be strengthened．And especially the causes of the morbidity and disability rate of children with no immunization of poliovirus vaccines being both higher than those of fully immunized children remain to be leamed We should heneeforthr keep on reinforcing the routine imnlunizatiou schedule．Enhancing the rate of vaccination and eradicating zero immunizatinn