Determination of Norwalk-like Viruses in Feces of Children with Nonrotavirus Diarrhea

Objective This study was made to understand the infection status of Norwalk-like virus-es in 90 rotavirus-negative stool samples tested by molecular biology from infants and pre-school children who Suffered from diarrhea．Methods Enzyme-linked immunosorbent assay (ELISA) was adopted to determine the antigen of Norwalk-like viruses．Results 6 cases of type I(G1)and 19 cas-es of type II (G2) Norwalk-like virus were detected in 90 stool samples，with a positive rate of 6.67％ and 21.11％，respectively，indicating significant difference between them．Conclusion The in-feetion of Norwalk-like viruses might be one of the most important factors that lead to diarrhea among infants and pre-school children in Wuhan city，typeⅡ Norwalk一like virus iS the main epidemic strain．