Clinical and epidemiological characteristics of 2 cases of thrombocytopenia syndrome accompanied by fever in Ningbo

Objective To understand the clinical and epidemiological characteristics of 2 cases of thrombocytopenia syndrome accompanied by fever in Ningbo and help the diagnosis and treatment of the disease. Methods The clinical and the epidemiological data were collected with standardized questionnaire from the first 2 cases occurred in Ningbo in May 2012 to conduct retrospective analysis. Results One case died duo to the severe illness and another one was cured. The clinical manifestations included acute onset, long time high fever, myalgia, enlarged superficial lymph nodes, progressive white cell and platelet reductions. The 2 cases were all old farmers who lived in wood and hilly areas, had histories of working in the fields or in the underbrush, and had histories of tick-bite. There were no secondary cases among the close contacts. Conclusion The clinical manifestations of thrombocytopenia syndrome accompanied by fever are complex, including multiple organ damage. The death may be related with shock, viral myocarditis, respiratory failure and multiple organ failure. The patients are usually the people who live in wood and hilly area, have histories of working in fields or in underbrush and have histories of tick-bite.