Immunization level of influenza in general population in Zhangzhou, Fujian, 2007-2011

Objective To understand the immunization level of influenza in general population in Zhangzhou, Fujian province, and provide evidence for the prevention and control of influenza. Methods A total of 550 serum samples were collected in general population in Zhangzhou from 2007 to 2011 and hemagglutination inhibition test was conducted to detect influenza virus antibody. Results The differences in antibody positive rates of Influenza A(H1N1), influenza A(H3N2), influenza B/Yamagata lineage and influenza B/Victorian viruses had statistical significance. The geometric mean titer(GMT) was 48.5, 9.9, 29.9 and 31.6 respectively, and the antibody protection rate was 19.8%, 23.6%, 21.1% and 7.5% respectively. Conclusion The antibody levels to the 4 influenza viruses were without protective effects in general population in Zhangzhou, indicating the potential of the local outbreak of influenza A(H1N1), influenza A(H3N2) and influenza B. It is necessary to strengthen the surveillance of influenza virus variants and antibody level in general population to predicate the incidence trend of influenza and provide evidence for the prevention and control of influenza.