Estimation of new HIV-1 infection in high risk groups with BED-CEIA in Zhejiang, 2010-2012

Objective To estimate the new infection rate of HIV-1 in high risk groups in Zhejiang province from 2010 to 2012. Methods New infection was detected by using 665 positive samples collected through HIV/AIDS sentinel surveillance and 4030 samples collected from newly reported confirmed cases in Zhejiang during this period with BED HIV-1 capture enzyme immunoassay (BED-CEIA). Results The new HIV-1 infection rate in men who have sex with men (MSM) was 3.52% (2.22%-4.83%) in 2010, 6.63% (4.65%-7.94%) in 2011 and 6.33% (4.83%-7.84%) in 2012,respectively. The proportion of positive samples in total BED tested samples was 27.08% in 2010, 26.09% in 2011 and 30.35% in 2012,respectively.The new infections in MSM accounted for 40.17% in 2011 and 42.05% in 2012 of total MSM cases. Conclusion The incidence of HIV-1 infection in MSM increased rapidly from 2010 to 2011, slightly decreased from 2011 to 2012, indicating that the prevalence of HIV-1 infection in MSM is still high in Zhejiang. It is very important to strengthen the intervention in MSM.