Surveillance for measles antibody level in healthy population in a district of Quzhou, Zhejiang

Objective To understand the measles neutralization antibody level in healthy population in Qujiang district of Quzhou, Zhejiang province and provide scientific evidence for the implementation of measles control measures. Methods Serum measles IgG antibodies were detected with ELISA in healthy people aged 15-45 years selected in Qujiang. The antibody geometric mean concentration (GMC) detection and 2-test were conducted too. Results Among the 363 serum samples, the positive rate of measles antibody was 96.69%, the GMC was 972.91 IU/L and the antibody protection rate was 66.67%. According to statistical analysis, there were significant differences in antibody protection rate among different age groups and among different years (P0.05). Conclusion The measles antibody level was high in healthy population in Qujiang in recent years. It is suggested to expand the coverage of measles vaccination to improve herd immunity for the control of measles.