Prevalence of non-alcoholic fatty liver and risk factors in office workers in Cixi, Zhejiang

Objective To understand the prevalence of non-alcoholic fatty liver and related risk factors in office workers in Cixi, Zhejiang province. Methods A total of 1256 office workers in Cixi received health examination, including biochemical detection and B-ultrasound detection, in our hospital from August 2012 to December 2012, and questionnaire survey were conducted among them. The risk factors of non-alcoholic fatty liver were analyzed by Chi-square test and logistic regression analysis. Results The prevalence of non-alcoholic fatty liver was 20.94%(251/1256). There was significant differences in gender (χ2=54.895), age (χ2=69.068), waist circumference (WC) (χ2=242.093), waist-to-hip ratio (WHR) (χ2=11.973), body mass index (BMI) (χ2=161.004), hyperuricacidemia prevalence (χ2=64.468), time of weekly exercise (χ2=15.370), eating out (χ2=4.322), night eating (χ2=39.527), way to travel (χ2=8.454), alanine aminotransferase (ALT) level (χ2=39.998), triglyeride (TG) level (χ2=100.860), high-density lipoproteins-cholesterol (HDL-C) level (χ2=99.393), diabetes prevalence (χ2=5.129) between case group and control group (Pχ2=3.559), aspartate aminotransferase (AST) level (χ2=3.693), cholesterol level (χ2=0.129), low density lipoprotein-cholesterol level (χ2=1.407) between the 2 groups(P>0.05). Logistic regression analysis indicated that gender, age, WC, BMI, hyperuricacidemia, time of weekly exercise, night eating, ALT level, TG level and HDL-C level were significant independent factors of non-alcoholic fatty liver. Conclusion The prevalence of non-alcoholic fatty liver was relatively higher in office workers in Cixi. The risk factors included age, WC, BMI, hyperuricacidemia, night eating, ALT level and TG. level The protective factors included gender (female), time of weekly exercise, HDL-C level.