Screening and treatment of Mycobacterium tuberculosis/HIV co-infection in Wenzhou, Zhejiang, 2011-2013

Objective To understand the performance of screening and treatment of Mycobacterium tuberculosis/HIV co-infection in Wenzhou, Zhejiang province, and provide evidence for the improvement of the co-infection. Methods The data about the screening and treatment of M. tuberculosis/HIV co-infection were collected from national tuberculosis reporting information system and annual reports of M. tuberculosis/HIV co-infection prevention and treatment in Wenzhou from 2011 to 2013 for statistical analysis. Results A total of 3694 cases/times of HIV infection were registered during this period, X-ray chest examination and sputum smear detection were conducted for 3534 cases (95.67%), and 45 tuberculosis(TB) cases were detected (1.27%). A total of 17 140 TB cases were registered, HIV test was conducted for 3067 cases (17.89%), and 13 cases of HIV infection were detected (0.42%). The difference in co-infection detection rate was statistical significant between the two detections (2=13.605, P0.01). Totally 58 cases of M. tuberculosis/HIV co-infection were detected. Among these cases, 53 received anti-TB treatment (91.38%), 32 received antiretroviral treatment (55.17%). Twenty five co-infection cases were reported to tuberculosis reporting information system, 9 were cured (36.00%), 2 were fatal (8.00%). The rate of successful treatment (cured and full course treatment) was 80.00% (20/25). Conclusion Cooperation between anti TB institution and CDC in screening of M. tuberculosis/HIV co-infection is an effective way for the early detection of M. tuberculosis/HIV co-infection, increasing of successful treatment rate and reducing of death rate.