Application of rabies vaccine and human rabies immunoglobulin in Quzhou, Zhejiang, 2010-2014

Objective To understand the application of rabies vaccine and human rabies immunoglobulin (HRIG) in the prevention and control of rabies in Quzhou, Zhejiang province, and provide evidence for the vaccine purchasing, use and stockpile management. Methods The data about the immunization of rabies vaccine and HRIG, including monthly vaccination dose, seasonal index and coverage rate, were collected in Quzhou during 2010-2014. Results A total of 103 888 doses of rabies vaccine were given during this period, and the vaccination doses increased with year. The annual vaccination doses peaked during May-October with the seasonal index 100%. Less vaccination doses were given during December-March with the seasonal index 80%. The HRIG injection rate was only 17.20% for grade III exposure, and the monthly injection doses and seasonal index varied obviously, similar to those of rabies vaccine. Conclusion More doses of rabies vaccine were give in summer and autumn than in winter and spring. The HRIG injection rate was low for grade III exposure. It is necessary to adjust the stockpile of the vaccine according to its seasonal need and strengthen the health education for the publics and the training for the health providers.