Epidemiology of hemorrhagic fever with renal syndrome in Guangzhou,2008-2014

Objective To understand the epidemiological characteristics of hemorrhagic fever with renal syndrome (HFRS) in Guangzhou from 2008 to 2014 and provide evidence for HFRS prevention and control. Methods Descriptive epidemiological analysis was conducted on the incidence data of HFRS and the surveillance data of HFRS host animals in Guangzhou during 2008-2014. Results A total of 783 HFRS cases were reported in Guangzhou during this period, including 3 deaths. The average annual morbidity was 0.92/lakh and the case fatality rate was 0.38%. The cases mainly occurred in spring and winter. The majority of the cases were middle aged adults (20-59 years old). The male to female ratio of the cases was 2.68:1. Most cases were the jobless, workers, people engaged in commercial service and farmers. The cases in Haizhu, Tianhe and Baiyun districts accounted for 27.46%, 18.65% and 13.67% respectively.The average rat density was 3.42% and Rattus norvegicus was predominant species. The rat serum sample detection indicated that the positive rate of IgG antibody was 14.39% and the positive rate of Hantaan virus antigen was 6.97%. Conclusion The incidence of HFRS was high in Guangzhou in recent years.It is necessary to take comprehensive prevention and control measures, including deratization and vaccination.