Relationship between triglyceride to high density lipoprotein cholesterol ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing

Objective To examine the association between triglyceride to high density lipoprotein cholesterol (TG/HDL-C) ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing. Methods Data were collected from Changping Health and Population Health Status Survey in 2013 with a standard questionnaire. Participants aged 18-79 years were divided into four groups according to quartiles of TG/HDL-C ratio in men and women, respectively. The outcome included diabetes, prediabetes and diabetes/prediabetes. Results A total of 3895 participants (1745 men and 2150 women) were eligible for final data analysis. A total of 413 adults with diabetes, 1016 adults with prediabetes, and 1429 adults with diabetes/prediabetes were recorded in the investigation. Multivariate logistic regression analysis indicated that the odds ratio (OR) of diabetes was 2.23 (95%CI: 1.35-3.68) and 2.36 (95%CI: 1.43-3.91), respectively, and the OR of diabetes/prediabetes was 1.38 (95%CI:1.01-1.87) and 1.80 (195%CI: 1.32-2.45), respectively, in men with TG/HDL-C ratio of 0.83-1.30 and 1.31, and the OR of prediabetes was 1.58 (95%CI: 1.13-2.21) in men with TG/HDL-C ratio 1.75 compared with men with TG/HDL-C ratio 0.66. In women, the OR of diabetes in those with TG/HDL-C ratio of 0.83-1.30 and 1.31 was 2.65 (95%CI: 1.56-4.49) and 3.72 (95%CI: 2.23-6.22) respectively, the OR of prediabetes was 1.60 (95%CI: 1.16-2.20) and 2.20 (95%CI: 1.59-3.04) respectively, and the OR of diabetes/prediabetes was 1.78 (95%CI:1.32-2.39) and 2.55 (95%CI:1.88-3.44) respectively compared with those with TG/HDL-C ratio 0.57. Conclusion Increased TG/HDL-C ratio was significantly associated with increased risk of prevalence of both diabetes and prediabetes.