Different region genotyping of Yersinia pestisin Inner Mongolia

Objective To study the geographic distribution of different region genotypes of Yersinia pestis isolated from different plague foci, hosts and media in Inner Mongolia. Methods A total of 307 strains isolated from three plague foci were selected for regional genotyping by using primers for 24 loci and software BioNumerics. Results A total of 13 genotypes were found, including 5 new genotypes(Gnm1-Gnm5). Nine genotypes, including the main genotype G11 (71.8%, 122/170), were found in Merionesunguiculatus plague focus in Inner Mongolia, and 6 genotypes were found in Spermophilus Dauricus plague focus in Songliaoplain, G10 (44.1%, 41/93) and G11 (35.5%, 33/93) accounted for high proportion. There were 4 genotypes in Lasiopodomysbrandtii plague focus in Xilingol grassland, G14 was predominant (90.9%, 40/44). Conclusion The geographic distribution of different region genotypes of Y. pestis was obvious in Inner Mongolia, the results has epidemiologic importance in analyzing the spread of Y. pestis and its genetic evolution in Inner Mongolia.