Analysis of prevalence of dyslipidemia and related risk factors in Uygur adults in Kashgar of South Xinjiang

To investigate the prevalence of dyslipidemia and related risk factors in Uygur adults in Kashgar of South Xinjiang. Methods Through cluster random sampling, Uygur adults aged ≥18 years were selected for analysis. Questionnaire survey, physical examination and laboratory detection were conducted for each participant. The population distribution of dyslipidemia was described, and risk factors were explored using non-conditional logistic regression analysis. Results Finally, 4 504 eligible participants were included in our analysis. The total prevalence of dyslipidemia was 50.84%, the prevalence of low high density lipoprotein cholesterol (HDL-C) was 46.65%, the prevalence of high triglyceride (TG) was 12.79%, the prevalence of high low density lipoprotein cholesterol (LDL-C) was 3.46% and the prevalence of high total cholesterol (TC) was 1.18%. The age-adjusted prevalence was 49.41%, 45.87%, 11.47%, 2.98% and 0.95%. The results of multivariable non-conditional logistic regression analysis showed that compared with females, males had 1.56 times higher risk of dyslipidemia (OR＝2.56, 95% CI: 2.22–2.95). Overweight (male:OR＝1.52, 95% CI:1.16–1.98; female:OR＝1.55, 95%CI:1.27–1.89), obesity (male:OR＝3.15, 95% CI:2.16–4.61; female:OR＝2.09, 95%CI:1.69–2.60), abdominal obesity (male:OR＝2.01, 95% CI:1.53–2.65; female:OR＝1.78, 95% CI:1.43–2.22）and diabetes in females (OR＝1.64, 95% CI:1.27–2.12) were the risk factors for dyslipidemia. Compared with the women with normal weight (BMI ＜24 kg/m²), the prevalence of dyslipidemia increased with the increase of BMI in both men and women (χ²＝384.69, P＜0.001). Overweight men (OR＝5.55, 95%CI: 4.03–7.63) and the obese men (OR＝11.77, 95% CI: 7.94–17.45) had higher risk for dyslipidemia (P _interaction ＝ 0.030), and the prevalence of low HDL-C also increased significantly (P_interaction＝0.039). Conclusion prevalence of dyslipidemia in Uygur adults in Kashgar was at relatively high level, especially low HDL-C. Synergic effect between BMI and gender had significant influence on prevalence of dyslipidemia and low HDL-C. More attention should be paid to overweight, obesity, and abdominal obesity, especially blood the lipid control in overweight and obese males.