Drug resistance of group A streptococcus and related factors in Beijing, 2016–2017

Objective To analyze the drug resistance characteristics of group A streptococcus and related factors in Beijing from 2016 to 2017.

Methods The minimum inhibitory concentrations of 12 antibiotics to group A streptococcus isolated from 16 districts in Beijing from 2016 to 2017 were tested.

Results A total of 243 group A streptococcus isolates were tested for drug resistance, and the sensitive rates of the isolates to cefotaxime, penicillin, meropenem and linezolid were 100%. The sensitive rates were 99.18% to cefepime and vancomycin, 97.53% to levofloxacin and 90.95% to ofloxacin. The sensitive rates to erythromycin, clindamycin and tetracycline were 1.65%, 2.06% and 2.88% respectively.

Conclusion The drug resistance rates of group A streptococcus to macrolides, clindamycin and tetracycline remained at high level in Beijing, while group A streptococcus kept sensitive to penicillin, cephalosporins and quinolones. Penicillin is still the preferred choice for the treatment of group A streptococcus infection.