Objective To analyze epidemiological characteristics of hand, foot and mouth disease (HFMD) in Jinhua, Zhejiang province, during 2011–2017 and provide evidence for the prevention and control of HFMD in Jinhua.
Methods The descriptive epidemiological analysis was conducted on the incidence data and the etiological detection results of HFMD.
Results A total of 88 157 HFMD cases, including 34 severe cases and 14 deaths, were reported in Jinhua during 2011 –2017, with an annual average incidence of 232.09/100 000. The epidemic of HFMD was characterized by high incidence every other year and annual double incidence peaks during April-July and during October-December. The difference in area distribution of HFMD cases was obvious, the incidence rate in urban area was 1.66–2.12 times higher than that in rural area. Most cases were children aged ≤5 years (96.10%), the high incidence age was observed in age group 1–3 years. Up to 97.06% of the severe cases and all the deaths occurred in children aged ≤3 years. More cases occurred in males than in females with a ratio of 1.47∶1. Most cases were children outside (69.60%) or in child care settings (28.14%). Etiological test of 3 789 mild cases samples showed that 2 126 were enterovirus positive (56.11%), of which the cases caused by enterovirus 71(EV71), coxsackie virus A16 (Cox A16) and other enteroviruses accounted for 24.60%, 18.77% and 56.63%, respectively. EV71 caused the majority of severe cases and deaths.
Conclusion HFMD had a wide distribution in Jinhua with obvious seasonality and population distribution difference. The prevention and control of HFMD in populations at high risk, high incidence seasons and key areas should be strengthened, and the vaccination in children aged ≤3 years should be further promoted. Furthermore, it is necessary to improve the surveillance schemes to increase the number of samples, sampling frequency and pathogenic detection items.
Home
DownLoad: