Epidemical characteristics of rifampicin-resistant tuberculosis in Hubei, 2007–2017

ObjectiveTo understand the epidemiological characteristics of rifampicin-resistant tuberculosis (RR-TB) in Hubei province from 2007 to 2017, and provide scientific evidence for drug-resistant TB prevention and control.

MethodsA retrospective analysis on the prevalence of RR-TB in Hubei was conducted using descriptive epidemiological method and GIS visualization technique.

ResultsFrom 2007 to 2017, a total of 3 012 RR-TB cases were registered in Hubei, including 2 669 cases of multidrug-resistant TB (MDR-TB), accounting for 88.61%. The annual registration rates of RR-TB and MDR-TB were 0.47/100 000 and 0.42/100 000 respectively, and the registration rates showed an upward trend (trends χ² ＝763.033, 506.672, P＜0.001). Among RR-TB cases, males accounted for 75.60%, females accounted for 24.40%. The cases were mainly young and middle-aged adults, those aged ＞45 years accounted for 23.97%. From 2007 to 2017, the RR-TB registration rates in different areas ranged from 0.03/100 000 to 1.26/100 000. The detection rate of RR-TB in the retreated cases was 28.84%, higher than that in the newly diagnosed cases (7.05%).

ConclusionThe registration rate of RR-TB increased with year in Hubei from 2007 to 2017, the cases were mainly young and middle-aged adults. Male cases and retreated cases accounted for higher proportions. It is suggested to strengthen the prevention and treatment of TB, as well as the screening, treatment and management of RR-TB to reduce the spread of drug-resistant TB.