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Chongshan Li, Zhi Li, Jing Wang, Jiayu Hu, Wei Tang, Yuying Yang, Yunyi Li, Yanji Yang, Xiaoxian Cui, Yulong Ye, Xi Zhang, Zhengan Yuan. Report of an imported measles outbreak caused by measles virus D8 in Shanghai, 2018[J]. Disease Surveillance, 2019, 34(7): 672-675. DOI: 10.3784/j.issn.1003-9961.2019.07.020
Citation: Chongshan Li, Zhi Li, Jing Wang, Jiayu Hu, Wei Tang, Yuying Yang, Yunyi Li, Yanji Yang, Xiaoxian Cui, Yulong Ye, Xi Zhang, Zhengan Yuan. Report of an imported measles outbreak caused by measles virus D8 in Shanghai, 2018[J]. Disease Surveillance, 2019, 34(7): 672-675. DOI: 10.3784/j.issn.1003-9961.2019.07.020
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Report of an imported measles outbreak caused by measles virus D8 in Shanghai, 2018

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    • Abstract
  • ObjectiveTo trace the source of an imported measles outbreak occurred in Shanghai in 2018, and analyze the molecular characteristics of the measles virus isolated.
    MethodsViral RNA was directly extracted from the throats swabs of the cases. The 676 nucleotides at COOH-terminal of nucleoprotein gene in measles virus were amplified by using one-step RT-PCR. The amplicons were sequenced by Sanger's to obtain the viral nucleotide sequences. Homology analysis was conducted to identify the viral genotype.
    ResultsThe cases in this outbreak came from a family, and 2 adult cases had a common outbound travel history within 21 d before the onset. The outbreak was caused by Measles virus D8.
    ConclusionBased on the results of epidemiologic investigation and laboratory tests, it was deduced that it was an imported measles outbreak caused by measles virus D8.
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