Progress in research of resistance and adaptation mechanisms of Campylobacter to antibiotics and biocides

Campylobacter, especially C. jejuni, is one of the three foodborne pathogens in the world. The production and spread of its antibiotic and biocide resistances is the focus of food safety. Compared with sensitive strains, after acquiring drug resistance, a series of physiological changes of bacteria, such as growth ability, in vitro and in vivo colonization and pathogenicity, will occur to develop adaptability for better survival under certain conditions. The strength of adaptability determines the risk of drug-resistant bacteria spreading in host and environment. This paper summarizes the resistance and adaptation mechanisms of Campylobacter to major antibiotics and biocides to provide theoretical support for the prevention and control of the prevalence and spread of antibiotic resistance of Campylobacter.