Progress in research of molecular detection of pathogens in bloodstream infection

The incidence rate of bloodstream infection (BSI) continues to increase around the world. The early identification and diagnosis of BSI has a great significance for clinical therapy. There are two kinds of molecular methods for rapid diagnosis of BSI: blood culture dependent detection and whole blood detection. Compared with the blood culture, whole blood detection can shorten the time needed and identify the pathogens which are difficult to culture, but the sensitivity needs to be improved. This paper summarizes the progress in the molecular detection of pathogens in bloodstream infection.