An investigation of a botulism poisoning event in Urumqi, Xinjiang

  Objective  To investigate the pathogenic factors and causes of a botulism poisoning event and provide evidence for the prevention and control of the similar events in the future.

  Methods  Field epidemiological survey was conducted through consulting medical records, interviewing relevant doctors and household survey. Laboratory test was done after collecting case stool samples and residual food samples for the detection of Clostridium botulinum.

  Results  Two poisoning cases were confirmed and admitted to hospital. After botulinum antitoxin A and B treatment, the symptoms were significantly alleviated. C. botulinum was isolated, which was identified as type A C. botulinum after detection of type A toxin gene by real time quantitative PCR. Type A botulinum toxin was detected in mouse experiments.

  Conclusion  This poisoning event was caused by homemade tempeh contaminated by C. botulinum type A. It is recommended to strengthen health education about the prevention of contamination in food production and storage. Medical institutions should prepare emergency medicines for food poisoning. Antitoxin serum should be used for the treatment of botulism poisoning.