Evaluation of the probiotic properties of Bacteroides vulgatus Bv46

  Objective  To evaluate probiotic potential of Bacteroides vulgatus Bv46.

  Methods  The Bv46 strain was tested on their tolerance to artificial gastric juices and bile salts. The Bv46 was assessed the hemolytic activity, antimicrobial susceptibility and gelatinase activity. Moreover, the probiotic properties of Bv46 were evaluated about auto-aggregation, hydrophobicity, adhesion to HT-29 cells, antimicrobial activity against pathogens, acid production and antioxidant properties.

  Results  It was 59.55% and 63.76% to the survival rates of Bv46 isolated from healthy people in simulated gastric juice and 0.3% bile salts respectively. Bv46 showed no haemolytic and gelatinase activities, and were only resistant to ampicillin and penicillin G. Bv46 showed medium auto-aggregation ability, but high hydrophobicity and medium adhesion to HT-29 cells. Moreover, Bv46 inhibited the growth of pathogenic Escherichia coli and Salmonella typhimurium. Furthermore, Bv46 produced short-chain fatty acids, and had antioxidant effects.

  Conclusion  The Bv46 is a potential probiotic.