Diarrhea pathogens spectrum in Guilin, Guangxi Zhuang Autonomous Region, 2019−2021

  Objective  To understand the pathogenic spectrum in diarrhea cases in Guilin Guangxi Zhuang Autonomous Region and provide evidence and support for the prevention and control of diarrhea.

  Methods  The stool samples were collected from diarrhea cases in designated hospitals in Guilin from January 2019 to June 2021 for the detection of 5 kinds of common viruses causing diarrhea and 17 kinds of common bacteria causing diarrhea.Then pathogen spectrum characteristics of diarrhea cases were analyzed.

  Results  In 385 samples, 9 kinds of pathogens were detected with an overall positive rate of 37.40%. The positive rate of bacterial pathogen was 12.99%, the positive rate of viral pathogen was 27.27%. The co-infection rate of two or more pathogens,mainly viruses, was 9.61%. There were no significant differences in pathogen detection rate among different age groups (P=0.510). The differences in pathogen detection rate were significant among different seasons. The pathogen positive rate in age group 0−2 years was highest (43.48%), followed by age groups 15−35 years (41.46%) and 36−60 years (38.78%). The infections were mainly caused by rotavirus, norovirus and halomonas.

  Conclusion  Multiple diarrhea pathogens were detected in Guilin. The incidence peak of bacterial diarrhea was in summer and the incidence peak of viral diarrhea was during spring-summer. Therefore, it is necessary to take targeted prevention and control measures and carry out diarrheal pathogen detection in clinical diagnosis and treatment to prevent and control the spread of diarrhea.