Objective To understand the factors associated with the willingness of non-occupational post-exposure prophylaxis (nPEP) use against HIV infection in general population, and provide scientific evidence for the development and implementation of AIDS intervention measures for general population.
Methods From January to June 2022, a questionnaire survey was conducted in Yangzhou, Jiangsu province. The data were collated and analyzed with software Excel 2019 and SPSS 26.0, logistics regression analysis was used to identify the variables associated with the nPEP use willingness in variables such as sociodemographic characteristics and AIDS awareness level. Multiple correspondence analysis was used to evaluate the relationship between the nPEP use willingness and the associated variables.
Results Only 20.8% of the 1 447 participants reported increased willingness to use nPEP, while 3.9% reported decreased willingness to use nPEP. The results of univariate analysis showed that the differences in nPEP use willingness were significant among general population with different age, monthly income, social capital, marriage history, HIV awareness level (all P<0.05). Logistic regression analysis showed that monthly income, gender, social capital and HIV awareness level were the factors influencing the nPEP use willingness in general population (all P<0.05); Multiple correspondence analysis showed that people with monthly income of less than 3000 yuan and higher HIV awareness had increased willingness to use nPEP; Men, people with high levels of social capital and monthly income of more than 6000 yuan had decreased willingness to use nPEP.
Conclusion The willingness to use nPEP against HIV infection the general population was related to various factors in Yangzhou. It is essential to further improve the awareness of HIV in general population, and promote and improve the access to nPEP for the purpose of reducing the spread of HIV.
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