浙江省湖州地区10680例女性人乳头瘤病毒感染及基因分型分析

李栋立 秦基取 钱福初 范晓娴

李栋立, 秦基取, 钱福初, 范晓娴. 浙江省湖州地区10680例女性人乳头瘤病毒感染及基因分型分析[J]. 疾病监测, 2015, 30(3): 209-213. doi: 10.3784/j.issn.1003-9961.2015.03.011
引用本文: 李栋立, 秦基取, 钱福初, 范晓娴. 浙江省湖州地区10680例女性人乳头瘤病毒感染及基因分型分析[J]. 疾病监测, 2015, 30(3): 209-213. doi: 10.3784/j.issn.1003-9961.2015.03.011
LI Dong-li, QIN Ji-qu, QIAN Fu-chu, FAN Xiao-xian. Analysis on human papilloma virus infection among 10 680 females in Huzhou, Zhejiang[J]. Disease Surveillance, 2015, 30(3): 209-213. doi: 10.3784/j.issn.1003-9961.2015.03.011
Citation: LI Dong-li, QIN Ji-qu, QIAN Fu-chu, FAN Xiao-xian. Analysis on human papilloma virus infection among 10 680 females in Huzhou, Zhejiang[J]. Disease Surveillance, 2015, 30(3): 209-213. doi: 10.3784/j.issn.1003-9961.2015.03.011

浙江省湖州地区10680例女性人乳头瘤病毒感染及基因分型分析

doi: 10.3784/j.issn.1003-9961.2015.03.011

Analysis on human papilloma virus infection among 10 680 females in Huzhou, Zhejiang

  • 摘要: 目的 了解浙江省湖州地区女性人乳头瘤病毒(human papilloma virus,HPV)亚型分布状况及年龄相关性,为本地区女性宫颈癌的防治及HPV疫苗的研制提供科学参考。方法 收集2011年1月至2013年12月于湖州市中心医院就诊的10 680份女性宫颈脱落细胞标本,以基因芯片方法进行HPV-DNA亚型检测及统计学分析。结果 10 680份标本,检出HPV阳性标本2865例,感染率为26.83%(2865/10 680)。亚型分布构成比排在前3位的分别为HPV16为17.52%(718/4099),HPV52为15.32%(628/4099),HPV58为12.42%(509/4099)。高危感染占82.41%(2361/2865),低危感染占8.90%(255/2865),高低危混合感染8.69%(249/2865);20岁年龄组3种感染类型感染率均最高。感染亚型以单一亚型感染为主(69.56%),单一亚型感染率最高的是45~49岁年龄组为77.56%,多重亚型感染率最高的是20岁年龄组为60.38%。结论 湖州地区门诊女性HPV感染率为26.83%,亚型以HPV16,18,52为主。20岁以下高感染率、高多重感染率说明HPV感染有低龄化多亚型化倾向,值得引起高度重视。
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出版历程
  • 收稿日期:  2014-09-04
  • 刊出日期:  2015-03-20

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