Abstract: Active surveillance for brucellosis started in 1980 in China and has been included in the national priority communicable disease surveillance since 2005. Brucellosis Surveillance is conducted in 21 permanent surveillance areas in 19 province(autonomous region,municipality). This paper summarizes the annual surveillance report of brucellosis in China (2005-2016)by Chinese Center for Disease Control and Prevention. In 2014,the reported case number of human brucellosis was highest in the history(57 222 cases),the morbidity rate was 4.22/100 000. The disease was only reported in 18 provinces (autonomous region,municipality)in 2003,but reported in all 31 provinces(autonomous region,municipality)in 2013. Brucellosis affected all the populations with occupational exposure. A total of 573 032 persons with occupational exposure were surveyed in 21 surveillance areas during the past 12 years,and serological test was performed for 196 636 persons,in whom 39 190 were sero-positive. The average positive rate was 18.11%. A total of 276 Brucella strains were analyzed,including 164 strains detected in surveillance areas and some strains sent for detection. Among these strains,Brucella melitensis accounted for 74%,and 16% the remained unidentified,which indicating that B. melitensis was the predominant pathogen causing brucellosis epidemics in China.