Abstract: Objective To understand the incidence and incidence trend of brucellosis in Zhangjiakou,Hebei province,and provide evidence for the prevention and control of brucellosis. Methods The surveillance data of brucellosis in Zhangjiakou during 2010-2017 were collected for a statistical analysis with software SPSS 20.0 to understand its absolute case growth, incidence trend and growth rate. Results A total of 16 626 brucellosis cases were reported in Zhangjiakou from 2010 to 2017. The annual incidence rate was 40.56/10 0 000,46.42/10 0 000,64.64/10 0000,77.64/100 000,55.57/100 000,32.69/100 000 and 17.33/100 000,respectively. The incidence rate increased during 2010-2014,but declined during 2015-2017. The seroprevalence was 16.61% and the average brucellosis prevalence was 10.14%. Br melitensis was predominant pathogen. Compared with adjacent areas,the differences in incidence had significance (P<0.05). The incidence was higher in western area than in eastern area. The incidence of brucellosis declined after effective intervention measures were taken in population at high risk. Conclusion The health education and behavioral intervention in population at high risk for brucellosis facilitate the control of brucellosis in Zhangjiakou,but brucellosis still occurs in Zhangjiakou and adjacent areas. Joint prevention and control of brucellosis still need to be strengthened.