Abstract: Objective To understand the epidemiological characteristics of laboratory confirmed measles cases in Haidian district, Beijing, during 2009-2012. Methods A descriptive epidemiological study was conducted to analyze laboratory confirmed cases measles reported to China Diseases Reporting Information System. Results The annual incidence of measles was in decline during this period except in 2010. A total of 333 laboratory confirmed measles cases were reported, accounting for 60.65% of the total (333/549), and 269 (80.78%) occurred during February-June. Among 328 cases with data available, the cases in age groups8 months and 20-39 years accounted for 58.85%, the cases in migrant population accounted for 74.09%. The cases with the immunization history of measles containing vaccine (MCV) accounted for 20.12%,the cases without the immunization history accounted for 42.68% and the cases with the unknown immunization history accounted for 37.20%. The isolation rate of measles virus in tested samples was 26.09% (6/23). All the isolated strains were belonged to genotype H1. Conclusion The measles incidence was at lowest level in Haidian during this period, but it is still necessary to further reduce the incidence of measles by improving timely vaccination of the first dose of MCV for infants aged 8 months, increasing routine vaccination coverage and conducting supplementary immunization activities as well as the adult immunization in migrant population.